Diazolidinyl urea (Germall II) is an antimicrobial preservative used in cosmetics.

Product information

CAS Number: 78491-02-8

Molecular Weight: 278.22

Formula: C8H14N4O7

Chemical Name: 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea

Smiles: OCNC(=O)N(CO)C1C(=O)N(CO)C(=O)N1CO

InChiKey: SOROIESOUPGGFO-UHFFFAOYSA-N

InChi: InChI=1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 55 mg/mL(197.68 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Kantor GR, et al. Acute allergic contact dermatitis from diazolidinyl urea (Germall II) in a hair gel. J Am Acad Dermatol. 1985;13(1):116-119.
2. Doi T, et al. The different decomposition properties of diazolidinyl urea in cosmetics and patch test materials. Contact Dermatitis. 2011;65(2):81-91.
3. Perret CM, et al. Contact sensitivity to diazolidinyl urea (Germall II). Arch Dermatol Res. 1989;281(1):57-59.

Products are for research use only. Not for human use.